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If you break the block, items will be dropped if you enable dropping, otherwise, they will be removed. After you break the block, items cannot be preserved on this location as the items are stored in block data, not on the location.
This video might clear things up: https://www.youtube.com/watch?v=PXQUX7EHZtU&list=PLAeL-oIFIEngE6jRgFYeFMfuj8WQsO3Ei&index=19